Pro Tools

When you open Pro Tools you will be greeted with a quick start window. 

The settings for bit depth should be on 24 Bit and the sample rate should be 48 kHz.
When you click ok you will be presented with a blank setup. So the first thing to do is add some tracks to this blank scene.
You have the choice of the type of track, mono/stereo and instrument or audio, and how many tracks you make at once. Instrument is different to audio because it has different midi settings. Let's say we decided to add 8 mono audio tracks to our scene.
You now have the ability to name you tracks. By default they will be 'Audio 1' or similar. They will also most likely not have the correct inputs. So we must assign our inputs to our tracks. There should be an 'I/O' drop down menu on each track. For your first track (for you first trick :D) you should assign input 1 to it. Let's say that input 1 is the kick drum. To avoid confusion of the tracks/inputs name the track Kick drum.
The last thing we should do is set a tempo for our composition. Just above the audio tracks there is a tab called bars and beats. Right click this and tempo should be in the list that appears. Click this and you should be able to set/change the tempo.

Congratulations! You've done it! How exciting. Now go and make music.